| 2024 | The Life Impossible | Barnes & Noble Best Books of the Year source ↗ (opens in a new tab) | Selection · Fiction | |
| 2021 | The Midnight Library | British Book Awards source ↗ (opens in a new tab) | Shortlist · Fiction Book of the Year | |
| 2021 | The Comfort Book | Goodreads Choice Awards source ↗ (opens in a new tab) | Nominee · Nonfiction | |
| 2020 | The Midnight Library | Goodreads Choice Awards source ↗ (opens in a new tab) | Winner · Fiction | |
| 2020 | The Midnight Library | New York Public Library Best Books source ↗ (opens in a new tab) | Selection · Best Books for Adults | |
| 2019 | How to Stop Time | Dublin Literary Award source ↗ (opens in a new tab) | Longlist · Fiction | |
| 2018 | How to Stop Time | British Book Awards source ↗ (opens in a new tab) | Shortlist · Fiction Book of the Year | |
| 2018 | The Truth Pixie | Goodreads Choice Awards source ↗ (opens in a new tab) | Nominee · Picture Books | |
| 2015 | Reasons to Stay Alive | Waterstones Book of the Year source ↗ (opens in a new tab) | Shortlist · Book of the Year | |
| 2015 | The Humans | Dublin Literary Award source ↗ (opens in a new tab) | Longlist · Fiction | |
| 2014 | The Humans | Edgar Allan Poe Awards source ↗ (opens in a new tab) | Nominee · Best Novel | |
| 2013 | The Humans | Goodreads Choice Awards source ↗ (opens in a new tab) | Nominee · Science Fiction | |
| 2011 | The Radleys | Alex Awards source ↗ (opens in a new tab) | Winner · Adult Books for Teens | |
| 2011 | The Radleys | British Book Awards source ↗ (opens in a new tab) | Shortlist · Popular Fiction | |