| 2020 | Fight of the Century | Goodreads Choice Awards source ↗ (opens in a new tab) | Nominee · History & Biography | |
| 2018 | Moonglow | Dublin Literary Award source ↗ (opens in a new tab) | Longlist · Fiction | |
| 2017 | Moonglow | Andrew Carnegie Medals for Excellence source ↗ (opens in a new tab) | Finalist · Fiction | |
| 2017 | Moonglow | Goodreads Choice Awards source ↗ (opens in a new tab) | Nominee · Historical Fiction | |
| 2017 | Moonglow | The Telegraph Best Books of the Year source ↗ (opens in a new tab) | Selection · Best Books | |
| 2016 | Moonglow | National Book Critics Circle Awards source ↗ (opens in a new tab) | Finalist · Fiction | |
| 2016 | Moonglow | Booklist Editors' Choice source ↗ (opens in a new tab) | Selection · Adult Books: Fiction | |
| 2016 | Moonglow: A Novel | Chicago Public Library Best of the Best source ↗ (opens in a new tab) | Selection · Best Books | |
| 2016 | Moonglow: A Novel | NPR Books We Love source ↗ (opens in a new tab) | Selection · Books We Love | |
| 2016 | Moonglow | The Globe and Mail Globe 100 source ↗ (opens in a new tab) | Selection · Fiction | |
| 2016 | Moonglow | The Wall Street Journal Best Books of the Year source ↗ (opens in a new tab) | Selection · Fiction | |
| 2016 | Moonglow | Paste Best Books of the Year source ↗ (opens in a new tab) | Selection · Fiction | |
| 2016 | Moonglow | New York Times 100 Notable Books source ↗ (opens in a new tab) | Selection · Fiction & Poetry | |
| 2016 | Moonglow | Washington Post Best Books of the Year source ↗ (opens in a new tab) | Selection · Notable Fiction | |
| 2014 | Telegraph Avenue | Dublin Literary Award source ↗ (opens in a new tab) | Longlist · Fiction | |
| 2013 | Telegraph Avenue | Andrew Carnegie Medals for Excellence source ↗ (opens in a new tab) | Longlist · Fiction | |
| 2012 | Telegraph Avenue | Los Angeles Times Book Prizes source ↗ (opens in a new tab) | Finalist · Fiction | |
| 2012 | Telegraph Avenue | Goodreads Choice Awards source ↗ (opens in a new tab) | Nominee · Fiction | |
| 2012 | Telegraph Avenue | Booklist Editors' Choice source ↗ (opens in a new tab) | Selection · Adult Books: Fiction | |
| 2012 | Telegraph Avenue | Chicago Tribune Best Books of the Year source ↗ (opens in a new tab) | Selection · Best Books | |
| 2012 | Telegraph Avenue | Vulture / New York Magazine Best Books of the Year source ↗ (opens in a new tab) | Selection · Best Books | |
| 2012 | Telegraph Avenue | The Irish Times Best Books of the Year source ↗ (opens in a new tab) | Selection · Books of the Year | |
| 2012 | Telegraph Avenue | Kirkus Best Books of the Year source ↗ (opens in a new tab) | Selection · Fiction | |
| 2012 | Telegraph Avenue | New York Times 100 Notable Books source ↗ (opens in a new tab) | Selection · Fiction & Poetry | |
| 2012 | Telegraph Avenue | Library Journal Best Books source ↗ (opens in a new tab) | Selection · More of the Best | |
| 2012 | Telegraph Avenue | Washington Post Best Books of the Year source ↗ (opens in a new tab) | Selection · Notable Fiction | |
| 2012 | Telegraph Avenue | Amazon Editors' Best Books of the Year source ↗ (opens in a new tab) | Selection · Top 100 | |
| 2009 | The Yiddish Policemen’s Union | Dublin Literary Award source ↗ (opens in a new tab) | Longlist · Fiction | |
| 2009 | Manhood for Amateurs | The Globe and Mail Globe 100 source ↗ (opens in a new tab) | Selection · Non-Fiction | |
| 2009 | Manhood for Amateurs | TIME Best Books of the Year source ↗ (opens in a new tab) | Selection · Nonfiction | |
| 2008 | The Yiddish Policemen's Union | Hugo Award (book categories) source ↗ (opens in a new tab) | Winner · Novel | |
| 2008 | The Yiddish Policemen's Union | Nebula Award (Novel, Novella and Andre Norton) source ↗ (opens in a new tab) | Winner · Novel | |
| 2008 | The Yiddish Policemen's Union | Locus Awards source ↗ (opens in a new tab) | Winner · SF Novel | |
| 2008 | The Yiddish Policemen's Union | John W. Campbell Memorial Award for Best Science Fiction Novel source ↗ (opens in a new tab) | Finalist · Best Science Fiction Novel | |
| 2008 | The Yiddish Policemen's Union | Edgar Allan Poe Awards source ↗ (opens in a new tab) | Nominee · Best Novel | |
| 2007 | The Yiddish Policemen's Union | BSFA Awards source ↗ (opens in a new tab) | Shortlist · Best Novel | |
| 2007 | The Yiddish Policemen's Union | Dashiell Hammett Prize source ↗ (opens in a new tab) | Nominee · Hammett Prize | |
| 2007 | The Yiddish Policemen’s Union | Booklist Editors' Choice source ↗ (opens in a new tab) | Selection · Adult Books: Fiction | |
| 2007 | The Yiddish Policemen’s Union | Vulture / New York Magazine Best Books of the Year source ↗ (opens in a new tab) | Selection · Best Books | |
| 2007 | The Yiddish Policemen's Union | The Economist Books of the Year source ↗ (opens in a new tab) | Selection · Fiction | |
| 2007 | The Yiddish Policemen's Union | Los Angeles Times Best Books of the Year source ↗ (opens in a new tab) | Selection · Fiction | |
| 2007 | The Yiddish Policemen’s Union | The Globe and Mail Globe 100 source ↗ (opens in a new tab) | Selection · Fiction | |
| 2007 | The Yiddish Policemen’s Union | New York Times 100 Notable Books source ↗ (opens in a new tab) | Selection · Fiction & Poetry | |
| 2007 | The Yiddish Policemen's Union | Washington Post Best Books of the Year source ↗ (opens in a new tab) | Selection · Notable Fiction | |
| 2007 | The Yiddish Policemen's Union | Amazon Editors' Best Books of the Year source ↗ (opens in a new tab) | Selection · Top 100 | |